Warnock was left fuming after his Cardiff side fell foul of a host of poor decisions in their 2-1 defeat by Chelsea on Sunday.
Two penalty appeals were waved away by referee Craig Pawson before Cesar Azpilicueta cancelled out Victor Camarasa’s opening goal with a header despite clearly being in an offside position.
Ruben Loftus-Cheek compounded the misery for Cardiff with a late header to seal all three points for Maurizio Sarri’s side.
Cardiff host City in midweek and a win for Pep Guardiola’s side would send them back to the top of the Premier League table and give them an advantage over rivals Liverpool in the race for the title.
Still reeling from the Chelsea defeat, a furious Warnock claimed it did not matter what side he picked as it would be the officials – who he also described as the worst in the world – that would ultimately decide the result.
“We keep getting knock-backs. I will probably play the U23s on Wednesday against Manchester City and try to keep it down to 10 or 11,” he said.
“It doesn’t matter who you play at the minute, it is who has a flag in his hand and who has a whistle.”
He added: ”It’s difficult because I am really flat. I am so proud of my players. To get let down by the officials… roll on VAR.
“We worked three weeks for this but to get let down by decisions… no major decisions went for us.
“They don’t realise what is at stake. If I was a Burnley or a Brighton fan, they will be absolutely loving it today.
“It’s not our fault an official can’t see that, it is the most obvious offside I have ever seen or the most certain penalty I have ever seen. What goes through my mind? Is it payback time for me over the years?
“It’s the best league in the world but the worst officials. They don’t understand what is at stake. They shouldn’t make mistakes at this level. Why am I working at 70 years of age for things like that to happen? It’s not very often I am lost for words.
“My players feel like they have been kicked in the teeth. We’ve been kicked so many times. I don’t deserve officials like that today. There is no excuse for that, it’s criminal.
“If my players feel like they look in the dressing room, that’s the end of our season. But how many times have we bounced back this season?”
Warnock’s comments are sure to anger Liverpool supporters after they watched their side beat Tottenham 2-1 at Anfield to go back to the top of the league table.
Jurgen Klopp’s side are looking for their first league title in 29 years and need City to slip up between now and the end of the season.